KAP1 anticorps (AA 1-50)

N° du produit ABIN7448920

Cet anticorps Lapin Polyclonal détecte spécifiquement KAP1 dans IHC et IF/ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour KAP1 anticorps (AA 1-50) (ABIN7448920)

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAP1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Détail du produit anti-KAP1 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-KAP-1 IHC Antibody, Affinity Purified

Homologie: Mouse,Bovine,Dog,Horse,Rabbit,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Northern white-cheeked gibbon,White-tufted-ear marmoset,Crab-eating macaque,Nine-banded armadillo,Small-eared galago,Olive baboon,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogène: Between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

ICC-IF: 1:100 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KAP1

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Autre désignation: KAP-1

Sujet: Background: KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.

ID gène: 10155

NCBI Accession: NP_005753

UniProt: Q13263

Pathways: Signalisation Hedgehog, Positive Regulation of Response to DNA Damage Stimulus